Kyrevi - Liposomal Retinol Cream

Liposomes
Liposomes are tiny spherical vesicles made from phospholipids - the same molecules that form cell membranes. When retinol is encapsulated within these liposomes, it gains several penetration advantages over conventional retinol creams.

Retinol
Retinol has been shown to reverse aging by accelerated cellular turnover, collagen restoration, DNA repair, melanin regulation, antioxidant network support, and improved skin barrier function. Please read below for more information.
How Liposomal Retinol Works
Liposomal retinol achieves deeper skin penetration through its unique delivery system that mimics and works with your skin's natural structure.
The Liposomal Advantage
Liposomes are tiny spherical vesicles made from phospholipids - the same molecules that form cell membranes. When retinol is encapsulated within these liposomes, it gains several penetration advantages over conventional retinol creams.
Enhanced Membrane Compatibility
Your skin's barrier consists of multiple layers of cells held together by lipid-rich membranes. Regular retinol in standard creams must work against this barrier, often getting trapped in the uppermost layers. Liposomal retinol, however, has phospholipid walls that are chemically similar to your skin cells' membranes. This similarity allows the liposomes to more easily merge with and pass through the skin barrier.
Protected Transport
The liposomal encapsulation protects retinol from degradation as it travels through the skin layers. Regular retinol is notoriously unstable and can break down when exposed to air, light, or the skin's natural pH. Inside liposomes, retinol remains stable and active until it reaches deeper skin layers where it's released.
Gradual Release Mechanism
Once liposomes penetrate into the skin, they gradually break down and release their retinol payload over time. This creates a sustained-release effect that delivers active retinol directly to target cells in the dermis, where collagen production and cellular renewal occur. Regular retinol creams typically deposit most of their active ingredient in the upper epidermis.
Size and Flexibility Benefits
Liposomes can be engineered to optimal sizes (typically 50-200 nanometers) that allow them to slip between skin cells more easily than larger molecules in conventional formulations. Their flexible, fluid structure also helps them deform and squeeze through tight cellular junctions.
This delivery system essentially turns your skin's natural barrier from an obstacle into a pathway, resulting in more effective retinol delivery where it can have the greatest anti-aging impact.